Video summary of the review article "Global increase in diabetes: implications for the control of tuberculosis" published in the open access journal Research and Reports in Tropical Medicine by Fisher-Hoch.
Abstract: Diabetes represents a greater threat to the global control of tuberculosis (TB) than previously appreciated, with the risk of reversing the achievements of several decades. An estimated 382 million people worldwide have diabetes, half of which are undiagnosed. Most live in low and middle income countries along with many of the two billion people infected with TB. Although the frequency of TB in type 1 diabetes was known for centuries, only recently have we observed the triplism of TB in type 2 diabetes, especially in high burden TB populations, such as Peru, Russia and the Republic. Popular of China. In India, it is estimated that diabetes has increased TB cases by 46% between 1998 and 2008. Diabetes is a greater long-term threat to tuberculosis control than the human immunodeficiency virus (HIV) / syndrome of acquired immunodeficiency (AIDS), since ten times more people affected by diabetes than HIV / AIDS in larger geographical areas. Diabetes in tuberculosis increases drug resistance, treatment failure and mortality, and may increase the spread of drug-resistant strains. Late or missed diagnosis ignores the transmission of TB and makes it difficult to control diabetes. Treatment adapted for patients with diabetes requires well-designed clinical trials. The framework of the World Health Organization (WHO) for the care and control of diabetes and TB needs better detection strategies. The determination of the best way to establish bidirectional detection is hampered by the lack of affordable and reliable methods. The recommendations include the education of health care providers, patients and communities. Structured diabetes programs with records and effective follow-up could be modeled and communicated with existing TB programs. Vital research should address new diagnostic tools, reduce cost and evaluate intervention strategies, as well as a better understanding of the impaired immune responses that make patients with diabetes more susceptible to TB and target targeted therapies. . The solutions will require the combination of good science, good decision-making, adequate financing and political will.
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Video credits to Dove Medical Press YouTube channel